ABSTRACT
Periodontal disease has been implicated as a risk factor for systemic diseases. There was a association between periodontal disease and serum albumin level in recent studies. The aim of this study was to evaluate the serum albumin concentration as a prognostic marker of the periodontal disease. In this cross-sectional study, 64 patients with chronic periodontitis, aged 20-50 years and 64 healthy control subjects with same age were selected. Dental and systemic stata were assessed for all subjects. Blood samples [2cc] were collected and COBASMIRA method was used to determine serum albumin level. The data were analyzed by One-Way ANOVA, Chi- square and t-tests. The mean serum albumin concentration was 5.05 +/- 2.7 gr/dl in chronic periodontitis and 4.40 +/- 0.39gr/dl in control group and the difference was significant [P=0.000]. Also there was a significant difference in albumin level between mild and moderate periodontitis [P=0.000]. Mean concentration of serum albumin level in periodontitis [mild, moderate, sever] was higher than control group